For whoever wants to save his life will lose it, but whoever loses his life for my sake and for the gospel will save it. -Mark 8:35

Saving our life is not a matter of security, happiness, wealth and power. Jesus tells us to live life according to His will and that would mean obedience and sacrifice. As we obey and sacrifice we work for His Kingdom.

Jesus' prayer, "your kingdom come, your will be done on earth as it is in heaven" is teaching our hearts to follow Jesus whatever it may cause because in the end, He will be exalted and so are we when He comes in the glory of His Father and with holy angels.